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BRAL1 Antibody

Catalog # Availability Size / Price Inquiry
AMM05636G 0.1 mg / $695

BRAL1 Antibody

Brand

Leading Biology

Catalog Number

AMM05636G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BRAL1 antibody.

Molecular Weight

37775 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

HAPLN2;

Isotype

IgG

Symbol

BRAL1

GeneID

UniProt ID

Function

Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan- associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid (By similarity).

Summary

BRAL1 Antibody: BRAL1 is a member a superfamily consisting of several highly homologous hyaluronan and proteoglycan binding link proteins. BRAL1 is predominantly expressed in brain tissue and spinal cord. Like other members in the link-module superfamily, BRAL1 contains an immunoglobulin-like fold and two proteoglycan tandem repeats (PTRs). Its mRNA expression pattern is similar to other lectican proteoglycans, suggesting that BRAL1 may act to stabilize the binding between the extracellular matrix molecule hyaluronan and brevican. Immunostaining of mouse brain showed BRAL1 expression at P20 in the white matter of the developing cerebellum and in myelinated fiber tracts in the adult brain, suggesting that expression starts when axonal myelination occurs.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of BRAL1 in human brain tissue lysate with BRAL1 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemical staining of human brain tissue using BRAL1 antibody at 2.5 μg/mL.

Immunofluorescence of BRAL1 in Human Brain cells with BRAL1 antibody at 20 μg/mL.

Specification

Quantity

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