> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > FEZ2 AntibodyBrand |
Leading Biology | Catalog Number |
APR11920G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FEZ2 antibody.
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Molecular Weight |
39666 Da
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
FEZ2;
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Function |
Involved in axonal outgrowth and fasciculation.
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Summary |
FEZ2 Antibody: Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IF, E
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Images |
Western blot analysis of FEZ2 in mouse brain tissue lysate with FEZ2 antibody at (A) 0.5, and (B) 1 μg/mL.
Immunofluorescence of human brain tissue using FEZ25 antibody at 5 μg/mL.
Immunofluorescence of FEZ2 in Human Brain cells with FEZ2 antibody at 5 μg/mL. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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