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T-cadherin Antibody

Catalog # Availability Size / Price Inquiry
APR10370G 0.1 mg / $695

T-cadherin Antibody

Brand

Leading Biology

Catalog Number

APR10370G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality T-cadherin antibody.

Molecular Weight

Predicted: 78, 84 kDa Observed: 85 kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Target

ENTPD3; At least two isoforms of T-cadherin are known to exist.

Isotype

IgG

Symbol

CD39L3

GeneID

UniProt ID

Function

Has a threefold preference for the hydrolysis of ATP over ADP.

Summary

T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Synonyms

T-cadherin Antibody: HB6, CD39L3, NTPDase-3, Ectonucleoside triphosphate diphosphohydrolase 3, CD39 antigen-like 3, NTPDase 3, ectonucleoside triphosphate diphosphohydrolase 3

Images

Western blot analysis of T-cadherin in 3T3 lysate with T-cadherin antibody at (A) 0.5 and (B) 1 μg/mL.

Immunofluorescence of T-cadherin in K562 cells with T-cadherin antibody at 20 μg/mL.

Immunofluorescence of T-cadherin in 3T3 cells with T-cadherin antibody at 2 μg/mL.

Specification

Quantity

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