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CTRP4 Antibody

Catalog # Availability Size / Price Inquiry
APR15633G 0.1 mg / $695

CTRP4 Antibody

Brand

Leading Biology

Catalog Number

APR15633G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTRP4 antibody.

Molecular Weight

35256 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

C1QTNF4; These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

Isotype

IgG

Symbol

CTRP4

GeneID

UniProt ID

Function

May act as a pro-inflammatory cytokine, that induces the activation of NF-kappa-B signaling pathway and up-regulates IL6 production.

Summary

CTRP4 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Synonyms

CTRP4 Antibody: CTRP4, ZACRP4, CTRP4, Complement C1q tumor necrosis factor-related protein 4, C1q and tumor necrosis factor related protein 4

Images

Western blot analysis of CTRP4 in rat brain cell lysate with CTRP4 antibody at (A) 1, (B) 2, and (C) 4 μg/mL.

Immunohistochemistry of CTRP4 in human brain tissue with CTRP4 antibody at 10 μg/mL.

Immunofluorescence of CTRP4 in human brain tissue with CTRP4 antibody at 20 μg/mL.

Specification

Quantity

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