> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Bcl-B AntibodyBrand |
Leading Biology | Catalog Number |
APG02226G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Bcl-B antibody.
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Molecular Weight |
21973 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion. Nucleus membrane
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
BCL2L10;
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Isotype |
IgG
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Symbol |
BCLB
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GeneID |
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UniProt ID |
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Function |
Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.
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Summary |
Bcl-B Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, ICC, E
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Synonyms |
Bcl-B Antibody: Boo, Diva, BCL-B, BCLB, Bcl-2-like protein 10, Anti-apoptotic protein NrH, Bcl2-L-10, BCL2-like 10 (apoptosis facilitator)
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Images |
Western blot analysis of Bcl-B in Jurkat lysate with Bcl-B antibody at 1 μg/ml in the (A) absence and (B) presence of blocking peptide.
Immunocytochemistry of Bcl-B in Jurkat cells with Bcl-B antibody at 10 μg/mL. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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