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Bcl-B Antibody

Catalog # Availability Size / Price Inquiry
APG02226G 0.1 mg / $695

Bcl-B Antibody

Brand

Leading Biology

Catalog Number

APG02226G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Bcl-B antibody.

Molecular Weight

21973 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion. Nucleus membrane

Host

Rabbit

Species Reactivity

Human

Target

BCL2L10;

Isotype

IgG

Symbol

BCLB

GeneID

UniProt ID

Function

Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.

Summary

Bcl-B Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, ICC, E

Synonyms

Bcl-B Antibody: Boo, Diva, BCL-B, BCLB, Bcl-2-like protein 10, Anti-apoptotic protein NrH, Bcl2-L-10, BCL2-like 10 (apoptosis facilitator)

Images

Western blot analysis of Bcl-B in Jurkat lysate with Bcl-B antibody at 1 μg/ml in the (A) absence and (B) presence of blocking peptide.

Immunocytochemistry of Bcl-B in Jurkat cells with Bcl-B antibody at 10 μg/mL.

Specification

Quantity

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