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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > P2Y1 Receptor (extracellular) Antibody

P2Y1 Receptor (extracellular) Antibody

Catalog # Availability Size / Price Inquiry
APR12693G 50 μl / $695

P2Y1 Receptor (extracellular) Antibody

Brand

Leading Biology

Catalog Number

APR12693G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality P2Y1 Receptor (extracellular) antibody.

Molecular Weight

42072 Da

Host

Rabbit

Species Reactivity

Human, Rat

Target

Peptide SDEYLRSYFIYSMC, corresponding to amino acid residues 207-220 of human P2Y1 Receptor (Accession P47900 ). 2nd extracellular loop.

GeneID

UniProt ID

Summary

The P2Y receptors belong to the G-protein coupled receptors superfamily.P2Y receptors mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDP) and regulate several physiologic responses, among them, cardiac function, platelet aggregation and SMC proliferation.1The mammalian P2Y family currently includes eight functional receptors; P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.2-4P2Y1 receptor is abundantly expressed in a number of tissues. In platelets, P2Y1 receptor is co-expressed with P2Y12 receptor, responsible for the initial shape change, aggregation, and rise in intracellular Ca2+ upon activation in response to ADP.5Abgent is please to offer a highly specific antibody directed againstan extracellular epitope of humanP2Y1 receptor.Anti-P2Y1 Receptor (extracellular)antibody (#AG1398) can be used in western blot analysisandindirect flow cytometryapplications, and has been designed to recognize P2Y1 from mouse, rat and human samples.

Form

Affinity purified antibody, Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~1:200-1:2000

Synonyms

P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1

Images

Western blot analysis of rat brain (lanes 1 and 4), Jurkat (lanes 2 and 5) and K-562 (lanes 3 and 6) lysates: 1-3. Anti-P2Y1 Receptor (extracellular) antibody ( APR12693G), (1:200). 4-6. Anti-P2Y1 Receptor (extracellular) antibody, preincubated with the control peptide antigen.

Indirect flow cytometry analysis of Jurkat (human acute T cell leukemia) living cells: Black Unstained cells. <span style="color: 99cc33">Black Cells stained + Anti-P2Y1 Receptor (extracellular) antibody ( APR12693G), (5 g/5x10<sup>5 </sup>cells).

Specification

Quantity

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