> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > 5-Hydroxytryptamine Receptor 1A AntibodyBrand |
Leading Biology | Catalog Number |
APG01373G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality 5-Hydroxytryptamine Receptor 1A antibody.
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Molecular Weight |
46429 Da
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Host |
Rabbit
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Species Reactivity |
Mouse, Rat
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Target |
Peptide KKSLNGQPGSGDWRRC, corresponding to amino acid residues 251-266 of rat 5-Hydroxytryptamine Receptor 1A (Accession P19327). 3rd intracellular loop.Will not recognize human 5-Hydroxytryptamine Receptor 1A.
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GeneID |
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UniProt ID |
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Summary |
Serotonin [5-hydroxytryptamine (5-HT1)] is an important neurotransmitter in the CNS that exerts its neuronal activity via 5-HT receptors.5-HT receptors are subdivided into seven families termed 5-HT1 through 5-HT7.1 The 5-HT receptor families belong to the G-Protein Coupled receptor superfamily with the exception of 5-HT3 receptor class which belongs to the ligand-gated ion channels. 2The 5-HT1 receptor class comprises of five different receptors (5-HT1A, 5-HT1B, 5-HT1D, 5-HT1e AND 5-HT1F) which share 41-63% overall sequence identity and couple preferentially to Gi/Go to inhibit cAMP formation.2The 5-HT1A receptor is the most widespread of all the 5-HT receptors. In the central nervous system, 5-HT1A receptors exist in the cerebral cortex, hippocampus, septum, amygdala and raphe nucelus in high densities, and was also demonstrated in a variety of tissues from various species.2,3Activation of 5-HT1A receptor decreases blood pressure and heart rate, involved in learning, memory, relieving anxiety and depression. 1,4 Abgent is pleased to offer a highly specific antibody directed against an intracellular epitope of the rat 5-Hydroxytryptamine Receptor 1A (5-HT1A). Anti-5-Hydroxytryptamine Receptor 1A antibody (#AG1012) can be used for western blot and immunohistochemistry applications. It has been designed to recognize 5-Hydroxytryptamine Receptor 1A from rat and mouse samples.
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Form |
Affinity purified antibody, Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC
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Dilution |
WB~~1:200-1:2000
IHC~~1:100
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Synonyms |
5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, Serotonin receptor 1A, Htr1a, 5ht1a
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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