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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody

Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody

Catalog # Availability Size / Price Inquiry
AMM06021G 100 μg / $545

Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody

Brand

Leading Biology

Catalog Number

AMM06021G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) antibody.

Molecular Weight

127179 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Chicken

Species Reactivity

Human, Mouse, Rat

Symbol

CD11B, CR3A

GeneID

UniProt ID

Function

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Form

Phosphate-buffered (10 mM) isotonic saline (0.9%, w.v) with sodium azide (0.02%, w/v) added as a preservative.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, ICC

Synonyms

Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b, ITGAM, CD11B, CR3A

Images

Mac-1 staining of the microglial cells in mouse cerebral cortex (red). Photo courtesy of Dr. Felix Eckenstein, University of Vermont.

Specification

Quantity

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