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HNF4A Antibody

Catalog # Availability Size / Price Inquiry
APR07782G 100 μg / $545

HNF4A Antibody

Brand

Leading Biology

Catalog Number

APR07782G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNF4A antibody.

Molecular Weight

52785 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human

Target

HNF4A

Isotype

Rabbit IgG

Symbol

HNF4, NR2A1, TCF14

GeneID

UniProt ID

Function

Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine.

Summary

HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in this protein have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Transcription factor HNF-4, Nuclear receptor subfamily 2 group A membre 1, Transcription factor 14, HNF4A, HNF4, NR2A1, TCF14

Images

Specification

Quantity

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