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DLG4 antibody - middle region

Catalog # Availability Size / Price Inquiry
APR11742G 50 μg / $545

DLG4 antibody - middle region

Brand

Leading Biology

Catalog Number

APR11742G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DLG4 antibody - middle region.

Molecular Weight

85kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, axon {ECO:0000250|UniProtKB:P31016}. Cell junction, synapse. Note=High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog

Symbol

PSD95

GeneID

UniProt ID

Function

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90, DLG4, PSD95

Images

WB Suggested Anti-DLG4 Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:1562500 Positive Control: HT1080 cell lysate

Specification

Quantity

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