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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SIGIRR antibody - C-terminal region

SIGIRR antibody - C-terminal region

Catalog # Availability Size / Price Inquiry
AMM07799G 50 μg / $545

SIGIRR antibody - C-terminal region

Brand

Leading Biology

Catalog Number

AMM07799G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SIGIRR antibody - C-terminal region.

Molecular Weight

25kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type III membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog

GeneID

UniProt ID

Function

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Synonyms

Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, Single immunoglobulin domain-containing IL1R-related protein, Toll/interleukin-1 receptor 8, TIR8, SIGIRR

Images

Liver

WB Suggested Anti-SIGIRR Antibody Titration: 0.2-1 μg/ml Positive Control: Jurkat cell lysate

Specification

Quantity

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