> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Tnik antibody - middle regionBrand |
Leading Biology | Catalog Number |
AMM08258G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Tnik antibody - middle region.
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Molecular Weight |
145kDa
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Recycling endosome. Cytoplasm, cytoskeleton Note=Associated with recycling endosomes and the cytoskeletal fraction upon RAP2A overexpression.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Yeast, Bovine, Guinea Pig, Dog
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Symbol |
Kiaa0551
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GeneID |
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UniProt ID |
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Function |
Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading (By similarity).
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Form |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Synonyms |
Traf2 and NCK-interacting protein kinase, 2.7.11.1, Tnik, Kiaa0551
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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