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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Phospho-Ser241 Munc18-1 Antibody

Phospho-Ser241 Munc18-1 Antibody

Catalog # Availability Size / Price Inquiry
APR09222G 100 μl / $545

Phospho-Ser241 Munc18-1 Antibody

Brand

Leading Biology

Catalog Number

APR09222G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-Ser241 Munc18-1 antibody.

Molecular Weight

65 KDa

Host

Rabbit

Species Reactivity

Mouse

Target

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser241 conjugated to KLH.

GeneID

UniProt ID

Summary

Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc18-1 is thought to be regulated by phosphorylation.

Form

Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~ 1:1000

Synonyms

Syntaxin-binding protein 1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, Stxbp1

Images

Western blot of mouse hippocampus lysate showing specific immunolabeling of the ~65k Munc18-1protein phosphorylated at Ser241. Phosphospecificity is shown in the second lane whereimmunolabeling is blocked by treatment of the lysate with lambda phosphatase (P-tase).

Specification

Quantity

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