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TGF-β1 Antibody

Catalog # Availability Size / Price Inquiry
APR10404G 100 μg / $545

TGF-β1 Antibody

Brand

Leading Biology

Catalog Number

APR10404G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TGF-β1 antibody.

Molecular Weight

44341 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

TGF-β1

Isotype

Rabbit IgG

Symbol

TGFB

GeneID

UniProt ID

Function

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

Summary

TGF-β(transforming growth factor-beta) is a family of multifunctional proteins. TGF-β was originally identified for its ability to induce the growth of normal rodent fibroblast in soft agar. It is now known that TGF-β is a potent growth inhibitor of many normal and transformed cell lines. It regulates normal cell growth, development and tissue remodeling following injury. TGF-β is produced as latent high molecular weight complexes. The activation of latent TGF-β is an important step in the regulation of its action.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Transforming growth factor beta-1, TGF-beta-1

Images

Western blot of mouse 3T3 cell lysate with TGF-β1 antibody

Specification

Quantity

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