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HDAC11 Antibody

Catalog # Availability Size / Price Inquiry
APR17772G 100 μg / $495

HDAC11 Antibody

Brand

Leading Biology

Catalog Number

APR17772G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HDAC11 antibody.

Molecular Weight

39183 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Note=Predominantly nuclear.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

HDAC11

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Summary

HDAC family are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns. These results s μggest that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

HD11 , Histone deacetylase 11

Images

Specification

Quantity

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