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DNAJC13 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR15780G 50 μg / $495

DNAJC13 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR15780G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DNAJC13 antibody (C-Terminus).

Molecular Weight

254415 Da

Cellular Localization

Antigen Cellular Localization: Early endosome. Early endosome membrane; Peripheral membrane protein. Endosome membrane

Host

Rabbit

Species Reactivity

Human, Mouse

Target

DNAJC13 antibody is human and mouse reactive. At least two siforms of DNAJC13 are known to exist; this antibody will detect both isoforms. DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.

Symbol

KIAA0678, RME8

GeneID

UniProt ID

Function

Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR (PubMed:18256511, PubMed:18307993). Involved in the regulation of endosomal membrane tubulation and regulates th dynamics of SNX1 on the endosomal membrane; via association with FAM21 may link the WASH complex to the retromer SNX-BAR subcomplex (PubMed:24643499).

Summary

Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR (PubMed:18256511, PubMed:18307993). Involved in the regulation of endosomal membrane tubulation and regulates th dynamics of SNX1 on the endosomal membrane; via association with FAM21 may link the WASH complex to the retromer SNX-BAR subcomplex (PubMed:24643499).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

IHC-P (10 μg/ml), WB (1 - 2 μg/ml),

Synonyms

DNAJC13, KIAA0678, RME8, RME-8

Images

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specification

Quantity

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