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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > LGALS3 / Galectin 3 Antibody (aa140-190)

LGALS3 / Galectin 3 Antibody (aa140-190)

Catalog # Availability Size / Price Inquiry
AMM06258G 50 μl / $495

LGALS3 / Galectin 3 Antibody (aa140-190)

Brand

Leading Biology

Catalog Number

AMM06258G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LGALS3 / Galectin 3 antibody (aa140-190).

Molecular Weight

26152 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Human MAC-2 / Galectin-3

Symbol

MAC2

GeneID

UniProt ID

Function

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Summary

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IF (1:50 - 1:200), IHC-P (5 μg/ml), WB (1:500 - 1:1000),

Synonyms

LGALS3, 35 kd lectin, 35 kDa lectin, CBP35, GAL3, Galactoside-binding protein, GALIG, IgE-binding protein, Laminin-binding protein, Gal-3, GALBP, MAC-2, Mac-2 antigen, L31, MAC2, CBP 35, Galactose-specific lectin 3, Galectin-3, L-31, Lectin L-29

Images

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Western blot of CBP 35(N174) pAb in extracts from HeLa cells.

Specification

Quantity

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