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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MAPK6 / ERK3 Antibody (aa461-510)

MAPK6 / ERK3 Antibody (aa461-510)

Catalog # Availability Size / Price Inquiry
APR17300G 50 μl / $495

MAPK6 / ERK3 Antibody (aa461-510)

Brand

Leading Biology

Catalog Number

APR17300G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAPK6 / ERK3 antibody (aa461-510).

Molecular Weight

82681 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Translocates to the cytoplasm following interaction with MAPKAPK5.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

p97 MAPK Antibody detects endogenous levels of total p97 MAPK protein.

Isotype

IgG

Symbol

ERK3, PRKM6

GeneID

UniProt ID

Function

Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).

Summary

Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

ELISA (1:5000), IF (1:100 - 1:500), IHC-P (10 μg/ml), WB (1:500 - 1:1000),

Synonyms

MAPK6, ERK-3, MAP kinase 6, MAPK 6, p97-MAPK, PRKM6, MAP kinase isoform p97, ERK3, HsT17250, p97MAPK

Images

Anti-MAPK6 / ERK3 antibody IHC staining of human heart.

Immunofluorescence of MCF7 cells, using p97 MAPK Antibody.

Western blot of extracts from K562 cells, using p97 MAPK Antibody.

Specification

Quantity

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