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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > C1orf187 / DRAXIN Antibody (C-Terminus)

C1orf187 / DRAXIN Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR11527G 50 μg / $495

C1orf187 / DRAXIN Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR11527G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality C1orf187 / DRAXIN antibody (C-Terminus).

Molecular Weight

38650 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Human C1orf187 / Neucrin/ Draxin. At least three isoforms of Neucrin are known to exist; this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.

Symbol

C1orf187

GeneID

UniProt ID

Function

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

Summary

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IF (20 μg/ml), IHC-P (5 μg/ml), WB (1 μg/ml),

Synonyms

DRAXIN, AGPA3119, UNQ3119, C1orf187, Neucrin

Images

Anti-C1orf187 / DRAXIN antibody IHC staining of human brain, cortex.

Immunofluorescence of NEUCRIN in mouse brain tissue with NEUCRIN antibody at 20 g/mL.

Western blot analysis of Neucrin in rat cerebellum tissue lysate with Neucrin antibody at 1 ug/ml.

Specification

Quantity

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