> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > C1orf187 / DRAXIN Antibody (C-Terminus)Brand |
Leading Biology | Catalog Number |
APR11527G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality C1orf187 / DRAXIN antibody (C-Terminus).
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Molecular Weight |
38650 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
Human C1orf187 / Neucrin/ Draxin. At least three isoforms of Neucrin are known to exist; this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.
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Symbol |
C1orf187
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GeneID |
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UniProt ID |
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Function |
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
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Summary |
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
IF (20 μg/ml), IHC-P (5 μg/ml), WB (1 μg/ml),
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Synonyms |
DRAXIN, AGPA3119, UNQ3119, C1orf187, Neucrin
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Images |
Anti-C1orf187 / DRAXIN antibody IHC staining of human brain, cortex.
Immunofluorescence of NEUCRIN in mouse brain tissue with NEUCRIN antibody at 20 g/mL.
Western blot analysis of Neucrin in rat cerebellum tissue lysate with Neucrin antibody at 1 ug/ml. |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
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