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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CYSLTR1 / CYSLT1 Antibody (aa131-180)

CYSLTR1 / CYSLT1 Antibody (aa131-180)

Catalog # Availability Size / Price Inquiry
AMM05820G 50 μl / $495

CYSLTR1 / CYSLT1 Antibody (aa131-180)

Brand

Leading Biology

Catalog Number

AMM05820G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYSLTR1 / CYSLT1 antibody (aa131-180).

Molecular Weight

38541 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Target

CYSLTR1 Antibody detects endogenous levels of total CYSLTR1 protein.

Isotype

IgG

Symbol

CYSLT1

GeneID

UniProt ID

Function

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.

Summary

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

ELISA (1:5000), IF (1:100 - 1:500), IHC-P (20 μg/ml), WB (1:500 - 1:1000),

Synonyms

CYSLTR1, Cys-LT1 receptor, CysLT(1), Cys-leukotriene-1 receptor, CYSLT1, CYSLT1R, CYSLTR, HG55, LTD4 receptor, HMTMF81, Cysteinyl lt1 receptor

Images

Anti-CYSLTR1 / CYSLT1 antibody IHC staining of human heart.

Immunofluorescence of COS7 cells, using CYSLTR1 Antibody.

Specification

Quantity

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