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KIAA0101 Antibody

Catalog # Availability Size / Price Inquiry
APR08091G 50 μg / $495

KIAA0101 Antibody

Brand

Leading Biology

Catalog Number

APR08091G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KIAA0101 antibody.

Molecular Weight

12kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm, perinuclear region. Note=Following DNA damage, localizes to DNA damage sites Colocalizes with centrosomes in perinuclear region

Host

Rabbit

Species Reactivity

Human

Target

Human KIAA0101

Symbol

NS5ATP9, PAF

GeneID

UniProt ID

Function

PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

Summary

PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (10 μg/ml)

Synonyms

PCNA-associated factor, Hepatitis C virus NS5A-transactivated protein 9, HCV NS5A-transactivated protein 9, Overexpressed in anaplastic thyroid carcinoma 1, OEATC-1, PCNA-associated factor of 15 kDa, PAF15, p15PAF, KIAA0101, NS5ATP9, PAF

Images

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specification

Quantity

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