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NDST2 Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR08635G 50 μg / $495

NDST2 Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR08635G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NDST2 antibody (N-Terminus).

Molecular Weight

101kDa

Cellular Localization

Antigen Cellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

NDST2 antibody is human, mouse and rat reactive. At least two isoforms of NDST2 are known to exist; this antibody will only detect the larger isoform. NDST2 antibody is predicted not to cross-react with other members of the NDST protein family.

Symbol

HSST2

GeneID

UniProt ID

Function

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate.

Summary

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IF (20 μg/ml), IHC-P (10 μg/ml), WB (1-2 μg/ml)

Synonyms

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2, 2.8.2.8, Glucosaminyl N-deacetylase/N-sulfotransferase 2, NDST-2, N-heparan sulfate sulfotransferase 2, N-HSST 2, Heparan sulfate N-deacetylase 2, 3.-.-.-, Heparan sulfate N-sulfotransferase 2, 2.8.2.-, NDST2, HSST2

Images

Western blot analysis of NDST2 in A-20 cell lysate with NDST2 antibody at 1 ug/ml in (A) the...

Immunofluorescence of NDST2 in Daudi cells with NDST2 antibody at 20 ug/ml.

Specification

Quantity

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