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EPLIN Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR15833G 50 μg / $495

EPLIN Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR15833G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EPLIN antibody (N-Terminus).

Molecular Weight

85kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Note=This cytoskeletal protein co- localizes with actin stress fibers and focal adhesion plaques

Host

Rabbit

Species Reactivity

Human

Target

LIMA1 antibody is human specific. At least four isoforms of LIMA1 are known to exist; this antibody will only detect the three largest isoforms.

Symbol

EPLIN, SREBP3

GeneID

UniProt ID

Function

Binds to actin monomers and filaments. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments.

Summary

Binds to actin monomers and filaments. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IF (20 μg/ml), IHC-P (10 μg/ml), WB (0.5-1 μg/ml)

Synonyms

LIM domain and actin-binding protein 1, Epithelial protein lost in neoplasm, LIMA1, EPLIN, SREBP3

Images

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specification

Quantity

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