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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > KIF2C / MCAK Antibody (aa50-100)

KIF2C / MCAK Antibody (aa50-100)

Catalog # Availability Size / Price Inquiry
APR17008G 50 μl / $495

KIF2C / MCAK Antibody (aa50-100)

Brand

Leading Biology

Catalog Number

APR17008G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KIF2C / MCAK antibody (aa50-100).

Molecular Weight

81kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Association with microtubule plus ends is also mediated by interaction with KIF18B. Centromeric localization requires the presence of BUB1 and SGOL2.

Host

Rabbit

Species Reactivity

Human, Rabbit, Horse

Target

Region between residue 50 and 100 of human Mitotic Centromere-Associated Kinesin using the numbering given in entry NP_006836.1 (GeneID 11004).

Symbol

KNSL6

GeneID

UniProt ID

Function

In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.

Summary

In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, IF, IP

Dilution

IF (1:250-1:1000), IHC-P (5 μg/ml), IP (2-5 μg/mg lysate)

Synonyms

Kinesin-like protein KIF2C, Kinesin-like protein 6, Mitotic centromere-associated kinesin, MCAK, KIF2C, KNSL6

Images

Anti-KIF2C / MCAK antibody IHC staining of human testis.

Specification

Quantity

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