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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > KIAA0652 / ATG13 Antibody (C-Terminus)

KIAA0652 / ATG13 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR08094G 50 μg / $495

KIAA0652 / ATG13 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR08094G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KIAA0652 / ATG13 antibody (C-Terminus).

Molecular Weight

57kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol. Preautophagosomal structure. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Recognizes human Autophagy-related protein 13 (ATG13), a 517 amino acid protein belonging to the ATG13 metazoan family.

Symbol

KIAA0652

GeneID

UniProt ID

Function

Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.

Summary

Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

IHC-P (5 μg/ml), WB (1 μg/ml),

Synonyms

Autophagy-related protein 13, ATG13, KIAA0652

Images

Western blot of rat heart tissue lysate probed with Rabbit anti-Mouse ATG13 at 1uM in the...

Anti-KIAA0652 / ATG13 antibody IHC staining of human prostate.

Specification

Quantity

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