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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PSPLA1 / Phospholipase A1 Antibody (C-Terminus)

PSPLA1 / Phospholipase A1 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
AMR09589G 50 μg / $495

PSPLA1 / Phospholipase A1 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

AMR09589G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PSPLA1 / Phospholipase A1 antibody (C-Terminus).

Molecular Weight

50kDa

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Rat

Target

Human PLA1A. At least three isoforms of PLA1A are known to exist; this antibody will detect all three isoforms.

Symbol

NMD, PSPLA1

GeneID

UniProt ID

Function

Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1- acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.

Summary

Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1- acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IF (20 μg/ml), IHC-P (10 μg/ml), WB (1-2 μg/ml)

Synonyms

Phospholipase A1 member A, 3.1.1.-, Phosphatidylserine-specific phospholipase A1, PS-PLA1, PLA1A, NMD, PSPLA1

Images

Immunofluorescence of PLA1A in human kidney tissue with PLA1A antibody at 20 g/mL.

Anti-PSPLA1 / PLA1A antibody IHC staining of human brain, cortex.

Immunofluorescence of PLA1A in human kidney tissue with PLA1A antibody at 20 ug/ml.

Specification

Quantity

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