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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SPTLC2 / LCB2 Antibody (C-Terminus)

SPTLC2 / LCB2 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR10227G 50 μg / $495

SPTLC2 / LCB2 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR10227G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPTLC2 / LCB2 antibody (C-Terminus).

Molecular Weight

63kDa

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Human SPTLC2. At least three isoforms of SPT2 are known to exist; this antibody will not detect isoform b. SPT2 antibody is predicted to not cross-react with SPT1.

Symbol

KIAA0526, LCB2

GeneID

UniProt ID

Function

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate.

Summary

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC, E

Dilution

ICC (10 μg/ml), IF (20 μg/ml), IHC-P (5 μg/ml), WB (1-2 μg/ml) ,

Synonyms

Serine palmitoyltransferase 2, 2.3.1.50, Long chain base biosynthesis protein 2, LCB 2, Long chain base biosynthesis protein 2a, LCB2a, Serine-palmitoyl-CoA transferase 2, SPT 2, SPTLC2, KIAA0526, LCB2

Images

Anti-SPTLC2 / LCB2 antibody IHC staining of human adrenal.

Immunocytochemistry of SPT2 in 3T3 cells with SPT2 antibody at 10 g/mL.

Immunofluorescence of SPT2 in 3T3 cells with SPT2 antibody at 20 g/mL.

Specification

Quantity

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