> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SPTLC2 / LCB2 Antibody (C-Terminus)Brand |
Leading Biology | Catalog Number |
APR10227G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SPTLC2 / LCB2 antibody (C-Terminus).
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Molecular Weight |
63kDa
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
Human SPTLC2. At least three isoforms of SPT2 are known to exist; this antibody will not detect isoform b. SPT2 antibody is predicted to not cross-react with SPT1.
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Symbol |
KIAA0526, LCB2
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GeneID |
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UniProt ID |
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Function |
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate.
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Summary |
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, ICC, E
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Dilution |
ICC (10 μg/ml), IF (20 μg/ml), IHC-P (5 μg/ml), WB (1-2 μg/ml) ,
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Synonyms |
Serine palmitoyltransferase 2, 2.3.1.50, Long chain base biosynthesis protein 2, LCB 2, Long chain base biosynthesis protein 2a, LCB2a, Serine-palmitoyl-CoA transferase 2, SPT 2, SPTLC2, KIAA0526, LCB2
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Images |
Anti-SPTLC2 / LCB2 antibody IHC staining of human adrenal.
Immunocytochemistry of SPT2 in 3T3 cells with SPT2 antibody at 10 g/mL.
Immunofluorescence of SPT2 in 3T3 cells with SPT2 antibody at 20 g/mL. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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