> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GRG4 / TLE4 Antibody (aa161-210)Brand |
Leading Biology | Catalog Number |
APR17770G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRG4 / TLE4 antibody (aa161-210).
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Molecular Weight |
84kDa
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Cellular Localization |
Antigen Cellular Localization:
Nucleus.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
TLE4 Antibody detects endogenous levels of total TLE4 protein.
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Symbol |
GRG4, KIAA1261
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GeneID |
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UniProt ID |
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Function |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).
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Summary |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
ELISA (1:20000), IHC-P (20 μg/ml), WB (1:500-1:1000)
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Synonyms |
Transducin-like enhancer protein 4, Grg-4, Groucho-related protein 4, TLE4, GRG4, KIAA1261
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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