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CASK Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
AMM05694G 50 μg / $495

CASK Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

AMM05694G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASK antibody (N-Terminus).

Molecular Weight

105kDa

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human

Target

Human CASK. At least six alternatively spliced transcript variants have been observed.

Symbol

LIN2

GeneID

UniProt ID

Function

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

Summary

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Synonyms

Peripheral plasma membrane protein CASK, hCASK, 2.7.11.1, Calcium/calmodulin-dependent serine protein kinase, Protein lin-2 homolog, CASK, LIN2

Images

Immunofluorescence of CASK in human brain tissue with CASK antibody at 20 ug/ml.

Western blot analysis of CASK in mouse brain tissue lysate with CASK antibody at 1 ug/ml in (A)...

Specification

Quantity

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