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CHML Antibody (aa128-177)

Catalog # Availability Size / Price Inquiry
AMM05753G 50 μl / $495

CHML Antibody (aa128-177)

Brand

Leading Biology

Catalog Number

AMM05753G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CHML antibody (aa128-177).

Molecular Weight

74kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol

Host

Rabbit

Species Reactivity

Human

Target

CHML Antibody detects endogenous levels of total CHML protein.

Symbol

REP2

GeneID

UniProt ID

Function

Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.

Summary

Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:1000), IHC-P (5 μg/ml), WB (1:500-1:1000)

Synonyms

Rab proteins geranylgeranyltransferase component A 2, Choroideremia-like protein, Rab escort protein 2, REP-2, CHML, REP2

Images

Western blot of extracts from COLO cells, using CHML Antibody.

Specification

Quantity

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