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SOX3 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR13468G 50 μg / $495

SOX3 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR13468G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SOX3 antibody (C-Terminus).

Molecular Weight

45kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Goat

Species Reactivity

Human, Mouse, Rabbit, Monkey

Target

Human SOX3.

GeneID

UniProt ID

Function

Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity).

Summary

Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:8000), IHC-P (3.75 μg/ml), WB (0.5-1.5 μg/ml)

Synonyms

Transcription factor SOX-3, SOX3

Images

SOX3 antibody (0.5 ug/ml) staining of Human Cerebral Cortex lysate (35 ug protein/ml in RIPA buffer).

Anti-SOX3 antibody IHC of human brain, cortex.

Specification

Quantity

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