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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > UCHL1 / PGP9.5 Antibody (aa171-220)

UCHL1 / PGP9.5 Antibody (aa171-220)

Catalog # Availability Size / Price Inquiry
APR13911G 50 μl / $495

UCHL1 / PGP9.5 Antibody (aa171-220)

Brand

Leading Biology

Catalog Number

APR13911G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UCHL1 / PGP9.5 antibody (aa171-220).

Molecular Weight

25kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor. Note=About 30% of total UCHL1 is associated with membranes in brain

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

PGP9.5 Antibody detects endogenous levels of total PGP9.5 protein.

GeneID

UniProt ID

Function

Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

Summary

Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:5000), IHC-P (5 μg/ml), WB (1:500-1:1000)

Synonyms

Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, 3.4.19.12, 6.-.-.-, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, UCHL1

Images

Western blot of extracts from 293 cells, using PGP9.5 Antibody.

Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex.

Anti-UCHL1 / PGP9.5 antibody IHC of human kidney.

Specification

Quantity

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