> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ATXN1 / SCA1 Antibody (aa742-791)Brand |
Leading Biology | Catalog Number |
APG03175G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATXN1 / SCA1 antibody (aa742-791).
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Molecular Weight |
87kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Colocalizes with USP7 in the nucleus
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Target |
Ataxin 1 (Ab-776) Antibody detects endogenous levels of total Ataxin 1 protein.
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Symbol |
ATX1, SCA1
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GeneID |
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UniProt ID |
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Function |
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
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Summary |
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, IF, E
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Dilution |
ELISA (1:5000), IF (1:100-1:500), IHC-P (5 μg/ml)
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Synonyms |
Ataxin-1, Spinocerebellar ataxia type 1 protein, ATXN1, ATX1, SCA1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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