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ATP11A Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR15084G 50 μg / $495

ATP11A Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR15084G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATP11A antibody (N-Terminus).

Molecular Weight

130kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Early endosome. Recycling endosome. Endoplasmic reticulum. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, predominantly located in the plasma membrane

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Human ATP11A

Symbol

ATPIH, ATPIS, KIAA1021

GeneID

UniProt ID

Function

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib.

Summary

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC, E

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Synonyms

Probable phospholipid-transporting ATPase IH, 3.6.3.1, ATPase IS, ATPase class VI type 11A, P4-ATPase flippase complex alpha subunit ATP11A, ATP11A, ATPIH, ATPIS, KIAA1021

Images

Immunocytochemistry of ATP11A in K562 cells with ATP11A antibody at 10 ug/ml.

Immunofluorescence of ATP11A in K562 cells with ATP11A antibody at 20 ug/ml.

Western blot analysis of ATP11A in K562 cell tissue lysate with ATP11A antibody at 1 ug/ml in...

Specification

Quantity

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