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CFTR Antibody (aa2-14)

Catalog # Availability Size / Price Inquiry
APG02557G 50 μg / $495

CFTR Antibody (aa2-14)

Brand

Leading Biology

Catalog Number

APG02557G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CFTR antibody (aa2-14).

Molecular Weight

168kDa

Cellular Localization

Antigen Cellular Localization: Early endosome membrane; Multi-pass membrane protein. Cell membrane. Note=In the oviduct and bronchus, detected on the apical side of epithelial cells, but not associated with cilia.

Host

Goat

Species Reactivity

Human, Monkey, Sheep, Bovine

Target

Human CFTR.

Symbol

ABCC7

GeneID

UniProt ID

Function

Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.

Summary

Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (2.5-5 μg/ml)

Synonyms

Cystic fibrosis transmembrane conductance regulator, CFTR, ATP-binding cassette sub-family C member 7, Channel conductance-controlling ATPase, 3.6.3.49, cAMP-dependent chloride channel, CFTR, ABCC7

Images

Anti-CFTR antibody IHC of human kidney.

Anti-CFTR antibody IHC of human prostate.

Specification

Quantity

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