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SCARA5 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
AMR09817G 50 μg / $495

SCARA5 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

AMR09817G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCARA5 antibody (C-Terminus).

Molecular Weight

54kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Target

Human SCARA5

GeneID

UniProt ID

Function

Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) (By similarity).

Summary

Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) (By similarity).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC, E

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Synonyms

Scavenger receptor class A member 5, Scavenger receptor hlg, SCARA5

Images

Immunocytochemistry of SCARA5 in HepG2 cells with SCARA5 antibody at 2.5 ug/ml.

Immunofluorescence of SCARA5 in HepG2 cells with SCARA5 antibody at 20 ug/ml.

Western blot of SCARA5 in human liver tissue lysate with SCARA5 antibody at 1 ug/ml.

Specification

Quantity

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