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Polyclonal Antibodies >
SCARA5 Antibody (C-Terminus)Brand |
Leading Biology | Catalog Number |
AMR09817G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SCARA5 antibody (C-Terminus).
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Molecular Weight |
54kDa
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass type II membrane protein
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Target |
Human SCARA5
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GeneID |
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UniProt ID |
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Function |
Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) (By similarity).
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Summary |
Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) (By similarity).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, ICC, E
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Dilution |
IHC-P (5 μg/ml), WB (1-2 μg/ml),
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Synonyms |
Scavenger receptor class A member 5, Scavenger receptor hlg, SCARA5
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Images |
Immunocytochemistry of SCARA5 in HepG2 cells with SCARA5 antibody at 2.5 ug/ml. Immunofluorescence of SCARA5 in HepG2 cells with SCARA5 antibody at 20 ug/ml. Western blot of SCARA5 in human liver tissue lysate with SCARA5 antibody at 1 ug/ml. |
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Specification |
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Quantity |
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