> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TMEM16B / ANO2 Antibody (N-Terminus)Brand |
Leading Biology | Catalog Number |
APR13753G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TMEM16B / ANO2 antibody (N-Terminus).
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Molecular Weight |
114kDa
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
Human ANO2
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Symbol |
C12orf3, TMEM16B
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GeneID |
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UniProt ID |
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Function |
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
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Summary |
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
IHC-P (5 μg/ml), WB (1-2 μg/ml),
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Synonyms |
Anoctamin-2, Transmembrane protein 16B, ANO2, C12orf3, TMEM16B
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Images |
Immunofluorescence of TMEM16B in Human Brain cells with TMEM16B antibody at 20 ug/ml. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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