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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TMEM16B / ANO2 Antibody (N-Terminus)

TMEM16B / ANO2 Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR13753G 50 μg / $495

TMEM16B / ANO2 Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR13753G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TMEM16B / ANO2 antibody (N-Terminus).

Molecular Weight

114kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Human ANO2

Symbol

C12orf3, TMEM16B

GeneID

UniProt ID

Function

Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.

Summary

Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Synonyms

Anoctamin-2, Transmembrane protein 16B, ANO2, C12orf3, TMEM16B

Images

Immunofluorescence of TMEM16B in Human Brain cells with TMEM16B antibody at 20 ug/ml.

Specification

Quantity

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