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IDE Antibody (Internal)

Catalog # Availability Size / Price Inquiry
APR07916G 50 μg / $495

IDE Antibody (Internal)

Brand

Leading Biology

Catalog Number

APR07916G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IDE antibody (Internal).

Molecular Weight

118kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell membrane. Secreted. Note=Present at the cell surface of neuron cells The membrane-associated isoform is approximately 5 kDa larger than the known cytosolic isoform

Host

Goat

Species Reactivity

Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog

Target

Human IDE.

GeneID

UniProt ID

Function

Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Summary

Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (3.75 μg/ml)

Synonyms

Insulin-degrading enzyme, 3.4.24.56, Abeta-degrading protease, Insulin protease, Insulinase, Insulysin, IDE

Images

Anti-IDE antibody IHC of human skeletal muscle.

Specification

Quantity

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