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DGAT2 Antibody (Internal)

Catalog # Availability Size / Price Inquiry
APR07572G 50 μg / $495

DGAT2 Antibody (Internal)

Brand

Leading Biology

Catalog Number

APR07572G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DGAT2 antibody (Internal).

Molecular Weight

44kDa

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet

Host

Goat

Species Reactivity

Human, Rabbit, Pig, Horse, Dog

Target

Human DGAT2. This antibody is not expected to cross-react with other DGAT members.

GeneID

UniProt ID

Function

Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT).

Summary

Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:128000), IHC-P (3.75 μg/ml), WB (0.3-1 μg/ml)

Synonyms

Diacylglycerol O-acyltransferase 2, 2.3.1.20, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, 2.3.1.76, Diglyceride acyltransferase 2, DGAT2

Images

Anti-DGAT2 antibody IHC of human liver.

Staining (0.5 ug/ml) of Human Liver lysate in the third lane (35 ug protein in RIPA buffer).

Specification

Quantity

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