> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HMOX1 / HO-1 AntibodyBrand |
Leading Biology | Catalog Number |
APR07774G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HMOX1 / HO-1 antibody.
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Molecular Weight |
33kDa
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Cellular Localization |
Antigen Cellular Localization:
Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat, Dog
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Symbol |
HO, HO1
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GeneID |
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UniProt ID |
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Function |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
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Summary |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P
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Dilution |
IHC-P (10 μg/ml), WB (1:1000),
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Synonyms |
Heme oxygenase 1, HO-1, 1.14.99.3, HMOX1, HO, HO1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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