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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Carboxylesterase 1 / CES1 Antibody (Internal)

Carboxylesterase 1 / CES1 Antibody (Internal)

Catalog # Availability Size / Price Inquiry
APG02362G 50 μg / $495

Carboxylesterase 1 / CES1 Antibody (Internal)

Brand

Leading Biology

Catalog Number

APG02362G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Carboxylesterase 1 / CES1 antibody (Internal).

Molecular Weight

63kDa

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum lumen

Host

Goat

Species Reactivity

Human

Target

Human CES1. This antibody is expected to recognise all three reported isoforms (NP_001020366.1; NP_001020365.1; NP_001257.4).

Symbol

CES2, SES1

GeneID

UniProt ID

Function

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.

Summary

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:8000), IHC-P (2.5 μg/ml), WB (0.03-0.1 μg/ml)

Synonyms

Liver carboxylesterase 1, Acyl-coenzyme A:cholesterol acyltransferase, ACAT, Brain carboxylesterase hBr1, Carboxylesterase 1, CE-1, hCE-1, 3.1.1.1, Cocaine carboxylesterase, Egasyn, HMSE, Methylumbelliferyl-acetate deacetylase 1, 3.1.1.56, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, REH, Serine esterase 1, Triacylglycerol hydrolase, TGH, CES1, CES2, SES1

Images

Antibody (0.03 ug/ml) staining of Human Liver lysate (35 ug protein in RIPA buffer).

Anti-CES1 antibody IHC of human lung.

Specification

Quantity

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