> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MYO5B / Myosin VB Antibody (N-Terminus)Brand |
Leading Biology | Catalog Number |
APR17508G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYO5B / Myosin VB antibody (N-Terminus).
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Molecular Weight |
214kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm {ECO:0000250|UniProtKB:P70569}.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Target |
Synthetic peptide corresponding to N-terminal residues of human Myosin-5B (Myosin Vb).
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Symbol |
KIAA1119
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GeneID |
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UniProt ID |
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Function |
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
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Summary |
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
ELISA (1 μg/ml), IHC-P (2.5 μg/ml), WB (1 μg/ml)
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Synonyms |
Unconventional myosin-Vb, MYO5B, KIAA1119
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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