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NR5A2 / LRH-1 Antibody (aa1-67)

Catalog # Availability Size / Price Inquiry
APR11151G 50 μl / $495

NR5A2 / LRH-1 Antibody (aa1-67)

Brand

Leading Biology

Catalog Number

APR11151G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NR5A2 / LRH-1 antibody (aa1-67).

Molecular Weight

61kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human

Target

Peptide corresponding to amino acids 1-67 of human CPF, member 2, variant 2

Symbol

B1F, CPF, FTF

GeneID

UniProt ID

Function

Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Summary

Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (1:50)

Synonyms

Nuclear receptor subfamily 5 group A member 2, Alpha-1-fetoprotein transcription factor, B1-binding factor, hB1F, CYP7A promoter-binding factor, Hepatocytic transcription factor, Liver receptor homolog 1, LRH-1, NR5A2, B1F, CPF, FTF

Images

Anti-NR5A2 antibody IHC of human pancreas.

Hela cell nuclear extract was resolved by electrophoresis, transferred to nitrocellulose, and...

Specification

Quantity

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