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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PLA2G6 / IPLA2 Antibody (aa557-576)

PLA2G6 / IPLA2 Antibody (aa557-576)

Catalog # Availability Size / Price Inquiry
AMM07230G 1 ea / $495

PLA2G6 / IPLA2 Antibody (aa557-576)

Brand

Leading Biology

Catalog Number

AMM07230G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLA2G6 / IPLA2 antibody (aa557-576).

Molecular Weight

90kDa

Cellular Localization

Antigen Cellular Localization: Isoform LH-iPLA2: Membrane; Peripheral membrane protein. Note=Recruited to the membrane-enriched pseudopod upon MCP1/CCL2 stimulation in monocytes

Host

Rabbit

Species Reactivity

Human, Hamster

Target

Hamster iPLA2 amino acids 557-576 (PRFNQNINLKPPTQPADQLV)1,2,3

Symbol

PLPLA9

GeneID

UniProt ID

Function

Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pseudopods.

Summary

Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pseudopods.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (1:200-1:400)

Synonyms

85/88 kDa calcium-independent phospholipase A2, CaI-PLA2, 3.1.1.4, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-containing protein 9, PNPLA9, PLA2G6, PLPLA9

Images

Anti-PLA2G6 antibody IHC of human skeletal muscle.

Specification

Quantity

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