> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DNASE2 / DNase II Antibody (aa347-360)Brand |
Leading Biology | Catalog Number |
APR07607G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DNASE2 / DNase II antibody (aa347-360).
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Molecular Weight |
40kDa
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Cellular Localization |
Antigen Cellular Localization:
Lysosome.
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
peptide corresponding to amino acids 347 to 360 of human DNase II precursor (2-4)
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Symbol |
DNASE2A, DNL2
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GeneID |
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UniProt ID |
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Function |
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
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Summary |
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P
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Dilution |
IHC-P (5 μg/ml), WB (1:500-1:1000),
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Synonyms |
Deoxyribonuclease-2-alpha, 3.1.22.1, Acid DNase, Deoxyribonuclease II alpha, DNase II alpha, Lysosomal DNase II, R31240_2, DNASE2, DNASE2A, DNL2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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