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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > IPAF / NLRC4 Antibody (C-Terminus)

IPAF / NLRC4 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR08020G 50 μg / $495

IPAF / NLRC4 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR08020G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IPAF / NLRC4 antibody (C-Terminus).

Molecular Weight

116kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cytoplasm, cytosol. Note=Cytoplasmic filaments

Host

Rabbit

Species Reactivity

Human

Target

synthetic peptide corresponding to amino acids near the C-terminus of human Ipaf

Symbol

CARD12, CLAN, CLAN1, IPAF

GeneID

UniProt ID

Function

Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis.

Summary

Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC

Dilution

IHC-P (5 μg/ml), WB (0.5-2 μg/ml),

Synonyms

NLR family CARD domain-containing protein 4, CARD, LRR, and NACHT-containing protein, Clan protein, Caspase recruitment domain-containing protein 12, Ice protease-activating factor, Ipaf, NLRC4, CARD12, CLAN, CLAN1, IPAF

Images

Immunocytochemistry of Ipaf in THP-1 cells with Ipaf antibody at 10 ug/ml.

Immunofluorescence of Ipaf in THP1 cells with Ipaf antibody at 10 ug/ml.

Anti-NLRC4 antibody IHC of human brain, cortex.

Specification

Quantity

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