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TRPC3 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR13808G 50 μg / $495

TRPC3 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR13808G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRPC3 antibody (C-Terminus).

Molecular Weight

96kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

14 amino acid peptide from near the carboxy terminus of human TRPC3

Symbol

TRP3

GeneID

UniProt ID

Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5- triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.

Summary

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5- triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IHC-P (5 μg/ml)

Synonyms

Short transient receptor potential channel 3, TrpC3, Transient receptor protein 3, TRP-3, hTrp-3, hTrp3, TRPC3, TRP3

Images

Immunofluorescence of TRPC3 in Mouse Heart cells with TRPC3 antibody at 20 ug/ml.

Western blot of TRPC3 in human brain tissue lysate with TRPC3 antibody at (A) 1 and (B) 2 ug/ml.

Anti-TRPC3 antibody IHC of human skeletal muscle.

Specification

Quantity

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