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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > FP / PTGFR Antibody (Extracellular Domain)

FP / PTGFR Antibody (Extracellular Domain)

Catalog # Availability Size / Price Inquiry
APR11933G 50 μg / $495

FP / PTGFR Antibody (Extracellular Domain)

Brand

Leading Biology

Catalog Number

APR11933G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FP / PTGFR antibody (Extracellular Domain).

Molecular Weight

40kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Target

Human PTGFR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

GeneID

UniProt ID

Function

Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.

Summary

Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (20 μg/ml)

Synonyms

Prostaglandin F2-alpha receptor, PGF receptor, PGF2-alpha receptor, Prostanoid FP receptor, PTGFR

Images

Anti-FP / PTGFR antibody IHC of human Skin, Melanoma.

Anti-FP / PTGFR antibody IHC of human Brain, Glioblastoma.

Anti-FP / PTGFR antibody IHC of human Ovary, Carcinoma.

Specification

Quantity

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