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Location: Home > Antigens, Antibodies, ELISA, Western Blo > Primary Antibody > Polyclonal Antibodies > MRGD / MRGPRD Antibody (Extracellular Domain)

MRGD / MRGPRD Antibody (Extracellular Domain)

Catalog # Availability Size / Price Inquiry
AMM06464G  In Stock 50 μg / $495

MRGD / MRGPRD Antibody (Extracellular Domain)

Brand

Leading Biology

Catalog Number

AMM06464G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MRGD / MRGPRD antibody (Extracellular Domain).

Molecular Weight

36kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein Note=Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine

Host

Rabbit

Species Reactivity

Human

Target

Human MRGPRD. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Symbol

MRGD

GeneID

UniProt ID

Function

May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

Summary

May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (9.3 μg/ml)

Synonyms

Mas-related G-protein coupled receptor member D, Beta-alanine receptor, G-protein coupled receptor TGR7, MRGPRD, MRGD

Images

Anti-MRGD / MRGPRD antibody IHC of human Brain, Glioblastoma.

Anti-MRGPRD antibody AMM06464G IHC of human brain, medulla.

Anti-MRGD / MRGPRD antibody IHC of human Skin, Melanoma.

Specification

Quantity

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