> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GPR68 / OGR1 Antibody (C-Terminus)Brand |
Leading Biology | Catalog Number |
APR16593G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GPR68 / OGR1 antibody (C-Terminus).
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Molecular Weight |
41kDa
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
Human GPR68. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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Symbol |
OGR1
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GeneID |
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UniProt ID |
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Function |
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity).
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Summary |
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, ICC, E
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Dilution |
IHC-P (5-7.5 μg/ml)
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Synonyms |
Ovarian cancer G-protein coupled receptor 1, OGR-1, G-protein coupled receptor 68, GPR12A, Sphingosylphosphorylcholine receptor, GPR68, OGR1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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